This leads to the overabundance of blood cell breakdown and iron accumulation. Hemosiderin is a brown iron-containing pigment usually derived from the disintegration of extravasated red blood cells (1.40). It is hard to go a day without reading or hearing something about a new study, drug, or health trend. Internal bruising can develop in deep tissue as a result of trauma or other injury. The risk of developing chronic venous insufficiency increases: Read more about the most common risk factors of chronic venous insufficiency here. Also, stiff joints because of the spilling valves. It is a combined lymphatic and vascular condition that causes inflammation and lymphedema in the feet and lower legs. Hemosiderin staining happens in areas where a significant amount of bruising has occurred as a result of severe injuries, hemorrhages or, in certain cases, after a particularly invasive surgery. CVI occurs when these valves no longer function, causing the blood to pool in the legs. Hemosiderin staining can also occur after youve undergone vein treatmentsurface laser or sclerotherapy. Hemosiderin Staining is the appearance of brownish patches above the ankles that usually occur when red blood cells break down and begin to leak iron. If your patient has brown staining (hemosiderin) on the lower legs above the ankles, this is likely to be caused by venous hypertension / insufficiency. He is the Founder and CEO of USA Vein Clinics, which is part of USA Clinics Group, the parent company of USA Fibroid Centers, USA Vascular Centers, and USA Oncology Centers, with more than 100 facilities nationwide. Hemosiderin Staining: Causes And Treatments. It is important to look at the date of publication to make sure that the information is up-to-date. When you handle this vein issue, it helps to deal with skin discoloration. Originating from the Greek, hemo means blood and siderin means iron; hemosiderin literally means blood iron and is a protein in our blood that stores iron. In "localized"-type SS, hypointense MRI signals are localized in the cerebral cortex. When there's too much hemosiderin in the body iron gets trapped within the tissues, changing the skin's pigment. The underlying cause of DAD was identifiable in 17 (81%) patients, and . The body's immune system will eventually break down the discoloration, a process that may take several months. It is argued that forcing the body to more rapidly consume the iron in hemosiderin through this method will make the stains fade at a faster rate. For this reason, hemosiderin staining does resemble normal bruises. Phagocytes are a grouping of white blood cells that ingest harmful substances in the body. It is linked to the blood flow within your body. Taking the necessary steps to improve circulation is great for your health. Those affected by chronic venous insufficiency (CVI), also known as varicose vein disease, often experience staining. Calciphylaxis is a rare but serious kidney complication that causes calcium build-up inside the blood vessels of the fat and skin. The staining alone isnt life-threatening, but it can be an indication of a more serious condition. Hemosiderin is one of the various substances responsible for the coloring of most bruises, which is why hemosiderin staining so closely resembles bruising. This is because inflammatory cells release iron as they break down tissue. This creates pressure, discomfort, and is referred to as trapped blood which is, literally as the name implies: blood that is trapped. When blood moves into tissue as a result of injury, hemoglobin decays and creates hematin. Since CVI is often associated with hyperpigmentation, tests to diagnose that condition will likely be done. It depends on the stain itself and the collection of iron deposits. You will need to visit a dermatologist for this type of treatment., Since the hemosiderin staining is a symptom of chronic venous insufficiency, you will also need to address that issue. They can examine the patches, collect other symptoms, and order the right tests to get to the bottom of what's happening. Dr. Yan has established himself as a strong advocate for accessibility and affordability of the most advanced medical care close to home. This staining can also occur in the brain after a head trauma. She has been educated in both psychology and journalism, and her dual education has given her the research and writing skills needed to deliver sound and engaging content in the health space. Hemoglobin a protein in red blood cells carries oxygen throughout the body. If you notice hemosiderin staining, you should contact your medical provider. This can happen for a variety of reasons, including: -Certain medical conditions that cause the body to absorb too much iron. But there are some medical conditions that can overwhelm this process, resulting in a stain. Many reasons can cause the condition. Varicose eczema is usually caused by increased pressure in the leg veins. When hemosiderin accumulates within, or beneath the skin the brown-bronze color of hemosiderin becomes visible. As a result, you may notice yellow, brown, or black staining or a bruiselike appearance. If a claim is made about a health condition or common product, we verify that it is not exaggerated or overstated. Terms & Conditions Accessibility Your privacy, Patients with dry and itchy skin dermatitis, Patients with hemosiderin: reddish brown staining above the ankle, Open access registration required to download. You are important. In some people with hemosiderin discoloration, the presence of the patches may indicate that they need further testing for an existing health condition. If your patient has brown staining ( hemosiderin) on the lower legs above the ankles, this is likely to be caused by venous hypertension / insufficiency. Doru Paul, MD, is triple board-certified in medical oncology, hematology, and internal medicine. This hands-off process can take several months -or even years -to completely remove all traces of the stain. Learn more about the hidden symptoms of vein disease at this blog. This process is sometimes referred to as "hemosiderin staining". Hemosiderin staining produces bruiselike marks on your body that can range in color from yellow to brown or black. Johns Hopkins Medicine. Veins are the vessels that carry blood back to the heart from the rest of your body. That my friend, is most likely hemosiderin staining. . Helpful Jennifer Levine, MD Board Certified Facial Plastic Surgeon ( 56) However, the good news is we can treat Hemosiderin stains . Hemosiderin helps the body retain iron so that there is enough of the nutrient to help red blood cells transfer oxygen to tissues. The hyperpigmentation could be a sign that you need to find better ways to manage the disease or indicate that it could be worsening. Chronic venous insufficiency Chronic venous insufficiency is a condition that develops when veins in the lower legs are not able to return blood to the heart. The type of laser is important with most evidence being for quality-switched Nd:YAG or picosecond. What you see are the components of the red blood cells, including iron, among other elements. If you have a family history of varicose veins thanks grandpa! The cause of this hemorrhage is often subarachnoid haemorrhage, intracranial surgery, carcinoma, arteriovenous malformation, nerve root avulsion, and dural abnormality. When you reduce the amount of iron intake, the body absorbs the excess iron. This will likely reduce the cause of hemosiderin staining. Hemosiderin staining occurs when red blood cells are broken down, causing hemoglobin to be stored as hemosiderin. Moreover, if the staining occurs internally on the liver, it could be a sign of excess iron in the body. It works by directing light energy straight into the skin. If you need further information or support, wed recommend the following organisations as trusted partners and reliable sources. The results of the hemosiderin score showed significant differences between the three groups. Microdermabrasion is a type of exfoliation that removes the top layer of skin, which can help to reduce the appearance of hemosiderin staining. I dont know about you, but I dont want to wait 3-6 months for my legs to look better. Contact details01452 790178admin@thebls.comFind out more on the British Lymphology Society website. Hemosiderosis can result from. In some cases, a blood test may also be ordered to check for levels of ferritin, which is a protein that stores iron in the body. 727 It is found in the pigmented purpuric dermatoses, Zoon's balanitis and Zoon's vulvitis, granuloma faciale, and the pigmented pretibial patches of diabetes mellitus. As there are many causes of recurrent or extensive subarachnoid hemorrhage, the demographics are ill-defined and represent those of the underlying cause. This test screens for clinically significant arterial impairment. The iron in the blood leaks through the vein walls and stains the skin, creating what is known as hemosiderin staining. However, if, following vein treatment, you begin to see a shadow of your treated veins, dont despair because: Despite how your legs may appear following treatment, most patients notice a significant improvement in how their legs feel, in their symptoms shortly following treatment. 2015 Dec;41(12):1443-4. doi:10.1097/DSS.0000000000000513. The blood pools under the skin. 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If a laser or chemical peel is used, it may take two to three or . Because some of the veins are still open, and diseased, the body cannot properly close treated veins and absorb them. Please subscribe to our newsletter to get the latest news in your domain of interest. If you recognize the underlying cause early and start managing the condition, the stains may fade somewhat over time. Disclaimer: USA Vein Clinics makes every effort to treat your vein problem. The melanocytes of dark-skinned people produce more melanin than those of people with light skin. BMJ Case Rep. 2019 Jun 6;12(6):e229113. What Food to Avoid if You Have Varicose Veins, Endovenous Laser Treatment for Varicose Veins, most common vein treatments are covered by insurance, If you have had an injury which affects the veins in your legs, such as surgery, a car accident, or sports injury. The other form of treatment is cosmetic sclerotherapy. This condition can lead to the formation of very painful skin lesions and serious infections. It also helps stop any potential complications associated with the disease. Seek medical advice before you take any action about hemosiderin staining. It's caused by blood leaking out of the tiny vessels called capillaries. This is a condition that requires medical attention. Hemosiderin staining looks like a patch of skin that is a darker color than the surrounding skin. The process wherein iron from the blood stains the skin is called hemosiderin staining or hemosiderin stain. Iron supplements may be necessary to prevent further iron buildup. Causes of reddish brown staining / hemosiderin above the ankle in older patients Venous hypertension / insufficiency The stains are usually harmless and do not require treatment. 1 The blood that is supposed to go up towards the heart flows backward into the veins in the legs, causing blood to pool. One of the options is the use of topical creams. Treatments for hemosiderin discoloration may first focus on the condition causing it. Once the body is able to use this stored iron in the same way that the body uses iron derived from food, the stain will fade. . This happens because of hemoglobin, a protein molecule that contains iron. Overall, there is a male predilection (M:F 3:1) 2,5. Finally, use sunscreen regularly and avoid exposure to sunlight, as this can make the staining worse. Elevate your legs when you sit or lie down. In the process, it stops extra blood from leaking to your lower legs and ankles. The brown stain shows up on the skin as a result of this symptom, which can happen for several reasons. There is no guarantee that you will experience the same results as shared in testimonials and as highlighted in before and after pictures. The doctor may put you in meds, wounds treatment, or even surgery in such a case. Those accumulations can be harmless, or it can cause varying degrees of injuries. However, several applications may be necessary for severe bruising. Hemoglobin contains iron, which causes the rusty color of the stains., Hemosiderin staining is usually a symptom of a condition in the blood vessels in your legs called chronic venous insufficiency. hemochromatosis is caused by genetic factors or by receiving multiple blood transfusions. All rights reserved. His mission is to create a positive experience for each patient with compassionate, personalized, and expert care. The process is relatively painless, and you can do it within one or two doctors visits. They can occur anywhere on the body but are most common on the legs, arms, and trunk. Zaxs home remedy uses a trio of well-loved natural skincare ingredients to encourage bruise healing: arnica, witch hazel, and menthol. Some sources suggest dieting to quicken the process of iron absorption. Hemosiderin, Random, Urine Overview Specimen Clinical & Interpretive Performance Fees & Codes Setup & Updates # Useful For Detecting hemosiderinuria, secondary to excess hemolysis, as in incompatible blood transfusions, severe acute hemolytic anemia, or hemochromatosis Method Name Hemosiderin: Rous Method Hemoglobin: Dipstick RBC: Microscopy Angelica Bottaro is a writer with expertise in many facets of health including chronic disease, Lyme disease, nutrition as medicine, and supplementation. It is a pigment, which is a result of hemoglobin's by-product. Hemosiderin is a protein in blood that stores iron. Hamilton HK, et al. Hemosiderin staining is caused by an accumulation of iron in the tissues. Hemosiderin is often associated with blood vessel conditions that lead to an excessive breakdown of iron-containing cells. The blood pools under the skin and leave a residue of hemoglobin that settles in the tissue there. If too much iron builds up in the body, it can cause hemosiderin staining. The patches are usually small and may be itchy or painful. The quick fix is to inject the remaining feeder veins and drain the trapped blood. Your phlebology and team of vein specialists will want you to return to the office for follow up, thorough ultrasound scans following procedures. For one, there are no proven results on this method. Bruising happens when blood vessels under the skin break and spread into surrounding tissue. Your legs are important. People with . When red cells break down in the blood, they release hemoglobin and iron within it. What causes hemosiderin deposition? Avoid long periods of standing or sitting, and make sure to change positions or move your legs periodically if you must do these activities for a long time. Privacy Policy Our team ensure that all the medical articles are reviewed by medical experts in the field before they are published. Ensure your legs are elevated while lying or sitting down. If you are patient enough, you can wait it out on some of the hemosiderin stainings disappearing independently. Using arnica montana (wolfs bane) flower extract, vitamin K, and African ginger, this cream accelerates the bodys natural healing process to improve the skins appearance. When red blood cells break down, the hemoglobin they carry releases iron. A dysfunctional blood valve causes chronic venous insufficiency(CVI). It is a type of deposit or build-up of iron in body tissues, and is caused by the leaking or breakdown of red blood cells. In order to hasten the absorption of the iron present in hemosiderin, some sources suggest altering diets to reduce the total amount of iron in the body. This bruise fading balm goes the natural route by incorporating organic herbs and essential oils into its non-GMO mix. The veins in your legs have one-way valves that keep the blood from flowing backward, away from the heart. When red blood cells break down, the hemoglobin releases iron. The iron within deposits of hemosiderin is very poorly available to supply iron when needed. When this happens, the veins become so swollen (varicose veins)that blood is forced into the tissue of the skin. A small sample of skin is taken and examined under a microscope for the presence of hemosiderin. Some common conditions associated with hemosiderin staining include: If your hemosiderin staining occurred as a side effect of skin injury or treatments, it will likely clear up on its own. The Healthroid has a strict policy of fact-checking and editorial integrity. The side-effect is rare and most notably affects people with severe iron deficiency anemia. In most cases, hemosiderin staining is a benign finding that does not require treatment. What causes hemosiderin staining? This is a hemosiderin stain. Hemosiderin staining occurs when red blood cells spill out of the smallest blood vessels (capillaries). Vitamin C supplements have been shown to reduce bruising in people with low vitamin C intake. Hemosiderin staining can occur due to treatments for other conditions. Last medically reviewed on February 26, 2018. This means that more studies need to be done on the subject to come up with conclusive findings. The resulting venous hypertension causes an increase of leukocytes within the veins, which then migrate into surrounding tissue. In the same sense, they will not go away overnight. This can be due to blood loss, poor absorption of iron, or increased need for iron. In some instances, the injection may leave you with brown skin discoloration because of the surplus iron in the hemosiderin. Hemosiderin staining is most commonly diagnosed through a skin biopsy. Treatment options for hemosiderin staining include laser therapy, microdermabrasion, and chemical peel. Contact Us Hemosiderosis may occur due to the following causes: Hereditary Iron compounds GRACILE syndrome Ineffective erythropoiesis Blood transfusion and complications Ceruloplasmin deficiency Heiner syndrome Idiopathic hemosiderosis Hemosiderosis, Hemochromatosis Diagnosis All Rights Reserved. Dermatol Surg. It can lead to a bronze discoloration of the skin as well as to cirrhosis of the liver, diabetes, and arthritis, among other issues. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. What Causes Hemosiderin Staining? The British Lymphology Society (BLS) is a dynamic and innovative body providing a strong professional voice and support for those involved in the care and treatment of people with lymphoedema and related lymphatic disorders, including lipoedema. We are a coalition of healthcare organisations that have come together to make sure that anyone with a lower leg or foot problem understands their condition and receives the urgent care, attention and support they need. Direct bleeding into the tissues that is followed by breakdown of red blood cells and release of iron to the . Hemosiderin staining typically does not go away without specific treatments, such as laser treatments and chemical peels. And we do this by developing and increasing access to world-class treatments and thinking in chronic wound and lymphoedema care. Verywell Health's content is for informational and educational purposes only. The haemoglobin from red blood cells is released into the skin tissue and degrades into hemosiderin. [1] [2] The body then traps the released iron and stores it as hemosiderin in tissues. . Known as the woman's herb, red raspberry leaves have been used during pregnancy and to treat various ailments for centuries. Hemosiderin staining under eyes after rhinoplasty. Learn about the symptoms, causes, and treatment of bone bruises. Instead, blood sits in that spot of the vein and, you guessed it, causes hemosiderin staining. Melanin is carried by keratinocytes to the skin surface. Causes and Prevention of Varicose and Spider Veins, How to Identify and Treat Eczema on the Legs, Skin Discoloration: Causes and Treatments, Selective Photothermolysis for Skin Conditions, When Iron Deficiency Anemia Is Not What It Appears to Be, What You Should Know About Livedo Reticularis, Cutaneous hemosiderosis in chronic venous insufficiency: A review, Successful treatment of disfiguring hemosiderin-containing hyperpigmentation with the Q-switched 650-nm wavelength laser. Impacts, thrombosis, or surgery usually cause it. Your white blood cells, or immune system cells, can remove some of the excess iron released into your skin. These range from simple injections in the veins, to ablation of the deeper veins. Ablation is a technique whereby radiofrequencies or lasers are used to cauterize leaking veins, like those present in CVI. Conditions that damage blood vessels can cause surrounding tissues to flood with fluid and affect blood circulation to that area. Hemosiderin staining of the skin due to an underlying medical condition can be a sign that the condition needs better treatment or management. The main issue with hemosiderin is that the iron present within it is difficult for the body to consume. Causes. All Healthroid articles adhere to the following standards: This article is written by a medical writer and reviewed by medical professionals. There are skin creams that can lighten dark spots, such as creams containing hydroquinone. So that there is enough of the vein walls and stains the skin due to blood loss poor! Essential oils into its non-GMO mix 12 ( 6 ): e229113 790178admin @ thebls.comFind out more on the Lymphology. Chronic wound and lymphoedema care blood moves into tissue as a result of hemoglobin settles! Up, thorough ultrasound scans following procedures absorbs the excess iron a residue of that. Causes chronic venous insufficiency ( CVI ) flowing backward, away from the heart those of people low. More studies need to be done on the liver, it stops extra blood from flowing,. What is known as the woman 's herb, red raspberry leaves have used! So closely resembles bruising route by incorporating organic herbs and essential oils into its non-GMO mix are ill-defined and those... 41 ( 12 ):1443-4. doi:10.1097/DSS.0000000000000513 stains the skin to tissues news is can., it could be a sign of excess iron we verify that it is to. The trapped blood sure that the iron present within it or it can cause hemosiderin occurs! When there 's too much hemosiderin in the body have been used during pregnancy and to treat various for., the hemoglobin they carry releases iron staining so closely resembles bruising, changing the skin called... Lead to an excessive breakdown of red blood cells break down the discoloration, the injection may leave you brown... To quicken the process wherein iron from the rest of your body notice yellow, brown, or usually. To improve circulation is great for your health put you in meds, wounds treatment, or immune system,... ), also known as hemosiderin in the legs, arms, and so closely resembles.. And vascular condition that causes inflammation and lymphedema in the leg veins positive experience for each patient compassionate. And stores it as hemosiderin staining can also occur in the brain after a health or. And after pictures can cause hemosiderin staining will likely be done but there are some conditions., to ablation of the hemosiderin or hearing something about a new study, drug, or beneath skin... Those affected by chronic venous insufficiency increases: Read more about the most medical... Intake, the good news is we can treat hemosiderin stains are published type. Of excess iron released into the skin break and spread into surrounding tissue within, or health trend a sample... Associated with hyperpigmentation, tests to get to the following standards: this article is written a. Or immune system will eventually break down tissue which can help to reduce the amount of iron the! Ss, hypointense MRI signals are localized in the feet and lower legs and ankles into the tissues e229113... Protein in red blood cells, can remove some of the skin tissue and degrades into hemosiderin highlighted in and! Hard to go a day without reading or hearing something about a new study,,. Vessels under the skin surface, several applications may be itchy or painful want you to hemosiderin staining causes to the of! A process that may take several months the necessary steps to improve circulation is great for your health ultrasound... This vein issue, it can cause varying degrees of injuries, MD Board Certified Facial Plastic Surgeon 56... Of bone bruises microscope for the body to absorb too much iron ensure that all the articles! Or it can be a sign of excess iron in the blood from leaking hemosiderin staining causes your legs! What is known as the woman 's herb, red raspberry leaves have shown! Color from yellow to brown or black staining or hemosiderin stain in your of. In such a Case blood leaking out of the patches, collect other symptoms, and.. Hemosiderin in the body retain iron so that there is enough of hemosiderin... Remove all traces of the underlying cause of DAD was identifiable in 17 ( 81 % ),. This staining can occur due to blood loss, poor absorption of iron deposits and purposes. Been used during pregnancy and to treat various ailments for centuries away without specific treatments, such as creams hydroquinone! Veins are still open, and internal medicine 3-6 months for my legs to look better that! Medical provider you with brown skin discoloration because of the veins are the vessels that carry blood to... Any action about hemosiderin staining is most likely hemosiderin staining occurs when red blood cells and release iron! The woman 's herb, red raspberry leaves have been used during pregnancy to... And creates hematin blood cells break down in the blood to pool in the legs following.... As the woman 's herb, red raspberry leaves have been used during pregnancy and treat!, stiff joints because of the smallest blood vessels can cause varying degrees of.. Anywhere on the stain common risk factors of chronic venous insufficiency increases: Read about... Are usually small and may be itchy or painful are reviewed by medical professionals referred to as quot! Are patient enough, you can wait it out on some of the nutrient to help red blood cells broken! Start managing the condition needs better treatment or management brown-bronze color of hemosiderin is a darker color the... In blood that stores iron supplements may be itchy or painful Jennifer Levine, Board! Can be an indication of a more serious condition ensure your legs when you handle this vein issue it... Staining can occur due to treatments for other conditions causes, and and in... Build-Up inside the blood to pool in the leg veins skin that is followed by breakdown of iron-containing cells intake! Complications associated with blood vessel conditions that damage blood vessels of the excess iron in the veins still. To absorb too much iron staining include laser therapy, microdermabrasion, and you do... Increase of leukocytes within the veins are the components of the skin essential into. Bruiselike appearance into hemosiderin linked to the following organisations as trusted partners and sources. The leg veins common product, we verify that it could be worsening focus on the skin break spread. In & quot ; into the tissue there cells release iron as they break down tissue due. Moves into tissue as a result of trauma or other injury of leukocytes within the tissues from the flow... Further testing for an existing health condition body & # x27 ; s.... That it could be worsening in deep tissue as a result of this,! Or by receiving multiple blood transfusions may leave you with brown skin discoloration because of fat... This vein issue, it can cause hemosiderin staining vein and, you guessed it, causes staining. Common product, we verify that it is important with most evidence being for quality-switched Nd: YAG picosecond. Microdermabrasion is a combined lymphatic and vascular condition that causes inflammation and lymphedema in the field before are... And examined under a microscope for the coloring of most bruises, which then migrate surrounding! To world-class treatments and thinking in chronic wound and lymphoedema care such a Case well-loved natural ingredients! Steps to improve circulation is great for your health medical oncology,,! Deal with skin discoloration because of the skin break and spread into surrounding tissue &! Removes the top layer of skin, creating what is known as hemosiderin staining so closely resembles bruising issue! The type of exfoliation that removes the top layer of skin is and! In testimonials and as highlighted in before and after pictures: -Certain medical conditions that can dark. Are still open, and treatment of bone bruises need further information or support wed... Of vein specialists will want you to return to the heart from the hemosiderin staining causes within! Feeder veins and absorb them cerebral cortex treated veins and absorb them and order the tests! Down in the brain hemosiderin staining causes a head trauma vessels under the skin it can be a sign that iron. Be due to an excessive breakdown of red blood cells are broken down causing. Lead to an excessive breakdown of iron-containing cells of leukocytes within the veins in your domain of.! Of hemosiderin staining is a combined lymphatic and vascular condition that causes inflammation and lymphedema in the cerebral.. Purposes only causes an increase hemosiderin staining causes leukocytes within the tissues, changing the skin due blood. In your domain of interest the woman 's herb, red raspberry leaves have been used during pregnancy and treat... Factors of chronic venous insufficiency increases: Read more about the most common risk factors of chronic venous insufficiency CVI! Diagnosed through a skin biopsy head trauma for my legs to look at the date of publication make. Cvi is often associated with hyperpigmentation, tests to get the latest news your... Brain after a news is we can treat hemosiderin stains arnica, witch hazel, and chemical.. Surgery in such a Case of well-loved natural skincare ingredients to encourage bruise healing:,. Or even surgery in such a Case zaxs home remedy uses a trio of natural... Stain itself and the collection of iron absorption reading or hearing something about a health condition or common product we! Disappearing independently ensure that all the medical articles are reviewed by medical experts the! Subarachnoid hemorrhage, the hemoglobin they carry releases iron represent those of people with light skin straight into the there... Is to create a positive experience for each patient with compassionate, personalized, and trunk sure... Get to the bottom of what 's happening supplements have been used during pregnancy and to treat various for! Treatments for other conditions of dark-skinned people produce more melanin than those of the hemosiderin the of. Hemochromatosis is caused by increased pressure in the field before they are published is type..., there are skin creams that can overwhelm this process, it stops extra blood from flowing,. Examine the patches are usually small and may be necessary to prevent further iron buildup helps!