If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia, or a malfunction of the autonomic nervous system. Lipitor contains the active drug atorvastatin. What is considered high cholesterol? In clinical studies of Zetia used with statin drugs to treat primary hyperlipidemia in adults and in children ages 10 years and older: It isnt known how long adults and children experienced muscle pain while taking Zetia with statin drugs in these clinical studies. At the end of the study, researchers found that: Mixed hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol and fats are cleared from your body. Currently GARD aims to provide the following information for this disease: Population Estimate: This section is currently in development. Porphyria patients are often overly sensitive to sunlight. To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. How long a medication remains good can depend on many factors, including how and where you store the medication. For more information about the effectiveness of Zetia for lowering your triglycerides, see the Zetia uses section above. Zetia isnt known to interact with grapefruit or any other foods. Statins, another medication for high cholesterol, are known to cause muscle-related side effects. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. A decrease in the transport of intestinal cholesterol to the liver reduces stores of hepatic cholesterol. Postural Tachycardia Syndrome (PoTS) is an abnormality of the autonomic nervous system (ANS). If you have liver problems, your liver may not work properly to remove medications such as Zetia from your body. For more information about Zetia, including details about its uses, see this in-depth article on the drug. They may be able to suggest ways to relieve this side effect. Most women describe brain zaps, also known as brain shivers or head shocks, as a repetitive electric-like sensation in the head. However, studies have found both Zetia and Lipitor to be effective for lowering cholesterol. To reduce your symptoms in . You can use the study as a second opinion to make health care decisions. But in studies, some people had to stop taking the drug due to feeling dizzy. Zetia contains the active drug ezetimibe. In most cases, these side effects should be temporary. Or they may recommend a product you apply to your skin, such as hydrocortisone cream. (A class of drugs is a group of medications that work in a similar way.) When you get Zetia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. If you have kidney problems, you may experience even higher levels of Zetia in your body. Or should I wait to see if I develop such side effects? What causes POTS? Cholesterol is a fatty substance found in the cells of your body. Liver problems. Weight gain isnt a side effect reported in clinical studies of Zetia. If you feel dizzy from Zetia, it may help to take your dose at bedtime. stomach pain. trouble in swallowing. No, stopping Zetia shouldnt cause any side effects. This article provides several useful tips on medication disposal. While taking Zetia, tell your doctor right away if you experience extreme muscle pain, muscle tenderness, or dark-colored urine. It can develop suddenly or maybe over time. However, 0.5% of adults and children who took Zetia with a statin drug experienced muscle pain so bothersome that they had to stop treatment. For HoFH, Zetia is FDA-approved to decrease levels of total cholesterol and LDL cholesterol. The only FDA-approved dosage of Zetia for children is 10 mg once a day. They often originate at the base of the skull and spreading on the back of the head and neck. Its primary metabolic pathway is via hepatic glucuronic conjunction. Blood pressure medications and water pills (diuretics) All blood pressure medications can cause ED, but thiazide diuretics and beta blockers are the most likely to do so. Rhabdomyolysis can also occur with statin drugs, and you may need to take Zetia with a statin. Total cholesterol is the overall amount of cholesterol found in your blood. You can take Zetia with or without food. Read more about these alternatives to traditional statin, Having high cholesterol puts you at risk for a heart attack or stroke. Some side effects are more common than others. Zetia is sometimes used with medications in the statin drug class. Treatment is targeted at relieving low blood volume or regulating circulatory problems that may cause the disorder. Tell them about all prescription, over-the-counter, and other drugs you take. Your FAQs Answered: Life Expectancy and Familial Hypercholesterolemia, Inherited High Cholesterol and Heart Disease: What to Ask Your Doctor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Heart Disease: How ApoB Cholesterol Tests Can More Accurately Identify Risks, Treatments, The 5 Best At-Home Cholesterol Tests in 2023, African Americans, Cholesterol, and the Risk of Heart Disease, Heart Health Breakthroughs: Top Advancements and Innovations of 2022, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, what dose of drug you were taking when you had the side effect, how soon after starting that dose you had the side effect, what your symptoms were from the side effect, what other medications you were also taking, any other information you feel is important, taking other medications, especially high dose statin drugs. Lipitor and Zetia belong to different drug classes. Primary hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. MNT is the registered trade mark of Healthline Media. You may also be having a reaction to all the medications mixed together. But if they become more severe or dont go away, talk with your doctor or pharmacist. However, you may need to avoid grapefruit if you take Zetia with a statin, another type of cholesterol medication. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. (A class of medications is a group of drugs that work in a similar way.) For example, in studies, some people had to stop taking the drug because their liver enzyme levels increased. Porphyrias have been associated with POTS symptoms (Stewart & Hensley, 1981). They can tell you about other medications that may work well for you. In the studies, total cholesterol levels: To learn how Zetia and the placebo affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Zetia and Lipitor have some similar side effects and others that vary. Talk with your doctor right away if you have fever or chills with your joint pain. Serious side effects from Zetia arent common, but they can occur. Zetia is available as a tablet that you take by mouth. If youre taking Zetia alone, you shouldnt need to take CoQ10. You may wonder how Zetia compares with other medications that are prescribed for similar uses. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. For more information on these side effects, see Side effect details below. Your risk of developing serious side effects may increase if you take Zetia with other medications to treat high cholesterol, such as statin drugs. Both Zetia and Lipitor come as tablets that are swallowed. You may find your symptoms are worse in the morning, and they may change from day to day. If you become pregnant while taking Zetia alone or with a statin drug, tell your doctor about your pregnancy right away. 5.8k views Answered >2 years ago. (For more information, see Liver problems in the Warnings for Zetia section above.). Learn more about how grapefruit may interact with medications. Zetia is a brand-name drug that contains the active drug ezetimibe. If you have multiple health conditions, your doctor may recommend other medications for you to take with Zetia. If youre using Zetia while sexually active with a female who could become pregnant, talk with your doctor about your birth control needs. These drugs havent been directly compared in clinical studies. Also tell them about any vitamins, herbs, and supplements you use. If you develop serious side effects while taking Zetia, call your doctor right away. Your doctor may have you stop your Zetia treatment if it isnt safe or effective for you. They can both be taken with or without food. Zetia is approved to treat certain forms of high cholesterol in adults when used with a low-cholesterol diet. Your doctor will also prescribe a low-cholesterol diet for you to follow while taking Zetia. If youve noticed memory problems while taking Zetia, talk with your doctor. This disorder affects the autonomic nervous system, which controls involuntary body functions such as body temperature and heart rate. And some may be easily managed, too. To learn about other mild side effects, talk with your doctor or pharmacist, or view Zetias prescribing information. Symptoms of atherosclerosis may include confusion, fatigue (lack of energy), trouble breathing, or pain in your chest, arms, or legs. The effect of Zetia, atorvastatin, or simvastatin on other types of cholesterol levels in this study isnt known. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. This list contains examples of serious side effects that can occur with both Zetia and Crestor (when taken individually). Dr. John Szawaluk answered. Zetia belongs to a class of drugs called cholesterol absorption inhibitors. In rare cases, taking Zetia with a statin drug may cause rhabdomyolysis (muscle breakdown). Zetia can cause mild or serious side effects. Most patients will need at least 64 to 80 ounces (8 to 10 cups) of hydrating liquids throughout the day, such as water, broth, juice, or decaffeinated tea. Crestor is part of the statin drug class. If taking your dose at bedtime doesnt help, or if dizziness becomes severe, tell your doctor. If you think youve taken too much of this drug, call your doctor. Instead, it belongs to a class of drugs called cholesterol absorption inhibitors. It only comes in a strength of 10 milligrams (mg). Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Crestor, or with both drugs (when taken individually). shaking and sweating. In studies, weight changes didnt occur in people who took the drug. Your doctor will determine the best dosage to fit your needs. Zetia and Crestor have some similar side effects and others that differ. Such an increase in heart rate may mean that your . However, your cholesterol levels may increase if you stop taking the drug. They may have suggestions depending on your weight and health goals. Bock's fainting spells are one of the hallmarks of POTS. Ezetimibe may cause side effects. shortness of breath or troubled breathing. Muscle problems were reported in clinical studies of adults and children who took Zetia with statin drugs. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. Merck, the manufacturer of Zetia, offers a Patient Assistance Program. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. It isnt safe to eat grapefruit or drink grapefruit juice while using statins. But, they can have side effects and might not be right for you. The generic is considered to be as safe and effective as the original drug. Across studies, researchers looked at different groups of people to evaluate whether Zetia was safe and worked for their condition. You can learn more about how we ensure our content is accurate and current by reading our. Can diet help improve depression symptoms? Your body uses cholesterol to make some vitamins, hormones, and fluids that help you digest food. Then theyll monitor whether the drug is working for you and whether you experience any side effects. Zetia generally costs less than Lipitor. What foods should I avoid while taking Zetia. For those who aren't familiar with POTS, it is an often-disabling neurological condition that causes your heart rate to rise a great deal when you are upright, and often blood pressure drops when you are upright (when it should be rising), and it causes fainting, fatigue, headache, nausea, face and hand tingling, and blood pooling in legs. Variable: Generally it is well tolerated but common side effects include:muscle aches , abdominal discomfort / diarrhea, fatigue. Before trying something new, its common to look for written reviews about the experiences of others. stuffy nose. Most of these side effects may go away within a few days or a couple of weeks. Qu H, et al. However, it isnt known how Zetia may affect these risks. However, animal studies dont always predict what will happens in humans. The phase IV clinical study analyzes which people take Zetia and have Constipation. Zetia has a well-documented safety profile. Yes, there are a few. The phase IV clinical study analyzes which people take Zetia and have Diarrhea. 6. Despite having lower total cholesterol than white people, African Americans are at greater risk of dying from heart disease. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . Symptoms of liver damage include: If you have any of the above symptoms of liver damage, tell your doctor right away. In studies, some people had to stop taking Zetia because of this side effect. But reviews and complaints about medications, including Zetia, may not be as reliable as other types of consumer reviews. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans, and millions more around the world. Nearly two years passed before Bock received an official diagnosis: postural orthostatic tachycardia syndrome, or POTS. These conditions can raise your risk of muscle problems while taking Zetia. These side effects may include diarrhea, muscle or joint aches, and cold symptoms, such as sore throat and congestion. These symptoms can be signs of an infection. Yes, treatment with Zetia should lower your triglycerides. If you have questions about weight changes while using Zetia, talk with your doctor. Its not clear if CoQ10 prevents muscle-related side effects when Zetia is taken with a statin, but it might help. Zetia shouldnt cause weight gain or weight loss. It also helps keep the drug from harming the environment. POTS is defined by its particular symptoms and an excessive increase in heart rate upon standing. Theyre a type of fat found in nuts, vegetable oils, and other plant-based foods. If you need to take these drugs together, take Zetia at least 2 hours before or 4 hours after taking cholestyramine. High cholesterol can raise your risk of heart disease. The expiration date helps guarantee that the medication is effective during this time. It may take about 2 weeks for your cholesterol levels to improve after you start taking Zetia. What are the serious side effects of Zetia? Learn more about some of the side effects that Zetia may cause. However, studies have found both Zetia and Crestor to be effective for lowering cholesterol. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. Ezetimibe can cause the breakdown of muscle tissue . If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. Causes of postural tachycardia syndrome (PoTS) It's not clear what causes postural tachycardia syndrome (PoTS). Increased liver enzyme levels are a possible side effect of Zetia. (2018). How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Homozygous familial hypercholesterolemia (HoFH), homozygous familial hypercholesterolemia (HoFH). Your doctor may stop your Zetia treatment if it isnt safe or effective for you. The Benary's Giants have large, double blossoms, 4 to 6 inches across, available in a rainbow of . Experience extreme muscle pain, muscle tenderness, or POTS Zetia in blood... 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