Monitor BP. Monitor Closely (3)serdexmethylphenidate/dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. only. Monitor BP. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Monitor for hypertension with concomitant use. Use Caution/Monitor. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. This means that you only need to take. Monitor Closely (1)methylphenidate will decrease the level or effect of moexipril by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of felodipine by pharmacodynamic antagonism. Comment: Green tea may include caffeine. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Risk of acute hypertensive episode. yerba mate increases effects of methylphenidate by pharmacodynamic synergism. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Methylphenidate may diminish antihypertensive effects. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)aluminum hydroxide decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of nifedipine by pharmacodynamic antagonism. Contraindicated. Use Caution/Monitor. Serious - Use Alternative (1)methoxyflurane increases toxicity of methylphenidate by Mechanism: unknown. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. methylphenidate will decrease the level or effect of trandolapril by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)methylphenidate will decrease the level or effect of penbutolol by pharmacodynamic antagonism. Risk of acute hypertensive episode. Monitor Closely (1)methylphenidate will decrease the level or effect of irbesartan by pharmacodynamic antagonism. Monitor Closely (1)promethazine, methylphenidate. Modify Therapy/Monitor Closely. Monitor Closely (1)oxytocin increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. dextroamphetamine increases effects of methylphenidate by pharmacodynamic synergism. Attention deficit hyperactivity disorder ( ADHD) medications are usually stimulants. Use Caution/Monitor. methylphenidate will decrease the level or effect of quinapril by pharmacodynamic antagonism. Monitor Closely (1)protriptyline, methylphenidate. methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. methylphenidate will decrease the level or effect of verapamil by pharmacodynamic antagonism. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. cariprazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Risk of acute hypertensive episode. bromocriptine, methylphenidate. Interaction specifically associated with Ritalin LA. Use Caution/Monitor. methylphenidate will decrease the level or effect of losartan by pharmacodynamic antagonism. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Trial of ADHD Medication with Fast Onset of Action, Entire Active Day Efficacy Initiated Methylphenidate may diminish antihypertensive effects. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. rabeprazole decreases effects of methylphenidate by enhancing GI absorption. Interaction more likely in certain predisposed pts. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Applies only to oral form of both agents. Contraindicated. Use Caution/Monitor. The generic drug name of Concerta is methylphenidate. Monitor Closely (1)methylphenidate will decrease the level or effect of diltiazem by pharmacodynamic antagonism. albuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor BP. Monitor BP. Are Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Significantly Linked to Childhood Allergies? Minor (1)desmopressin increases effects of methylphenidate by pharmacodynamic synergism. Avoid or Use Alternate Drug. Monitor BP. Interaction more likely in certain predisposed pts. Use Caution/Monitor. Monitor Closely (1)molindone increases toxicity of methylphenidate by pharmacodynamic antagonism. Mechanism: pharmacodynamic synergism. only. Avoid or Use Alternate Drug. methylphenidate will decrease the level or effect of penbutolol by pharmacodynamic antagonism. Monitor BP. Monitor Closely (1)methylphenidate will decrease the level or effect of enalapril by pharmacodynamic antagonism. Methylphenidate may diminish antihypertensive effects. Applies only to oral form of both agents. Contraindicated (1)benzphetamine increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Monitor Closely (1)cimetidine decreases effects of methylphenidate by enhancing GI absorption. Serious - Use Alternative (1)doxapram increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Applies only to oral form of both agents. Comment: Potential for additive CNS effects. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)cocaine topical increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Monitor BP. methylphenidate will decrease the level or effect of isradipine by pharmacodynamic antagonism. While Concerta and Ritalin have the same active ingredient, they work in different ways. Use Caution/Monitor. Most Use Caution/Monitor. maprotiline, methylphenidate. aluminum hydroxide decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Monitor Closely (1)norepinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Serious - Use Alternative (1)ergoloid mesylates, methylphenidate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Interaction more likely in certain predisposed pts. Monitor Closely (1)methylphenidate will increase the level or effect of phenytoin by unknown mechanism. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. trifluoperazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Capsule with multilayer beads; 40% of dose in the immediate-release layer and 60% in the extended-release layer (2nd peak at 7-8 hrs) 12 hours. Closely monitor blood pressure with concomitant use of esketamine nasal with stimulants. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor BP. Use Caution/Monitor. Applies only to oral form of both agents. Avoid or Use Alternate Drug. provider for the most current information. pirbuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Contraindicated. Other (see comment). To view formulary information first create a list of plans. Use Caution/Monitor. linezolid increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. ethanol increases levels of methylphenidate by enhancing GI absorption. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Methylphenidate may diminish antihypertensive effects. Methylphenidate may diminish antihypertensive effects. fluphenazine, methylphenidate. informational and educational purposes only. thioridazine, methylphenidate. methylphenidate will decrease the level or effect of valsartan by pharmacodynamic antagonism. Applies only to oral form of both agents. Individual plans may vary Applies only to oral form of both agents. Monitor BP. Modify Therapy/Monitor Closely. methoxyflurane increases toxicity of methylphenidate by Mechanism: unknown. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Applies only to extended release formulation. phendimetrazine increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Modify Therapy/Monitor Closely. dobutamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Mechanism: unknown. Monitor Closely (1)prochlorperazine, methylphenidate. diethylpropion increases effects of methylphenidate by pharmacodynamic synergism. perphenazine, methylphenidate. Monitor BP. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Most Use Caution/Monitor. Use Caution/Monitor. methylphenidate will increase the level or effect of dronabinol by pharmacodynamic synergism. Monitor Closely (1)aripiprazole increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Concerta releases about a third of its active compound in the morning and about 2/3 in the afternoon. Other (see comment). Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Other (see comment). Modify Therapy/Monitor Closely. Monitor Closely (1)levalbuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. methylphenidate will decrease the level or effect of perindopril by pharmacodynamic antagonism. fenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. methylphenidate will decrease the level or effect of ramipril by pharmacodynamic antagonism. loxapine inhaled increases toxicity of methylphenidate by pharmacodynamic antagonism. procarbazine increases effects of methylphenidate by pharmacodynamic synergism. Ritalin LA, Aptensio XR, Concerta, Metadate, Metadate CD, Metadate ER, Methylin, Quillivant XR, QuilliChew ER, Cotempla XR-ODT, Jornay PM, Adhansia XR, Relexxii, encoded search term (methylphenidate (Ritalin%2C Concerta)) and methylphenidate (Ritalin, Concerta), German 'Island' Aids Children and Adolescents With Addiction, FDA Warns of Websites Selling Adderall Illegally, Stimulants May Not Improve Academic Learning in Children With ADHD, ADHD Exacts Higher Mental Health Toll vs Autism in Adults, Attention Deficit Hyperactivity Disorder (ADHD). Risk of V tach, HTN. Use Caution/Monitor. Use Caution/Monitor. epinephrine racemic and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. serdexmethylphenidate/dexmethylphenidate and methylphenidate both decrease sedation. Monitor BP. Use Caution/Monitor. Contraindicated. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Minor/Significance Unknown. Contraindicated. Avoid or Use Alternate Drug. ibuprofen/famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Methylphenidate may diminish antihypertensive effects. Methylphenidate may diminish antihypertensive effects. benzphetamine increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Mechanism: pharmacodynamic synergism. Applies only to oral form of both agents. Monitor Closely (1)methylphenidate will decrease the level or effect of phenoxybenzamine by pharmacodynamic antagonism. nizatidine will increase the level or effect of methylphenidate by increasing gastric pH. Methylphenidate may diminish antihypertensive effects. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Avoid or Use Alternate Drug. Sympathomimetics can antagonize the activity of some antihypertensive agents. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Risk of acute hypertensive episode. Applies only to oral form of both agents. dexlansoprazole decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (1)hydrocodone, methylphenidate. desipramine, methylphenidate. Use Caution/Monitor. Monitor Closely (1)dopexamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. ergoloid mesylates, methylphenidate. Monitor Closely (1)methylphenidate will decrease the level or effect of nimodipine by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. Monitor Closely (1)methylphenidate will decrease the level or effect of quinapril by pharmacodynamic antagonism. Monitor BP. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. levalbuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. commonly, these are "preferred" (on formulary) brand drugs. Other (see comment). Other (see comment). CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Monitor BP. methylphenidate will decrease the level or effect of nifedipine by pharmacodynamic antagonism. Use Caution/Monitor. Monitor Closely (1)methylphenidate will increase the level or effect of dronabinol by pharmacodynamic synergism. Use Caution/Monitor. Other (see comment). Use Caution/Monitor. quetiapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate increases effects of warfarin by unspecified interaction mechanism. Modify Therapy/Monitor Closely. Monitor BP. Contraindicated. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Caffeine is a CNS-stimulant and additive effects may be seen when coadministered with other CNS stimulants. methylphenidate will decrease the level or effect of diltiazem by pharmacodynamic antagonism. Mechanism: unknown. Bupropion. epinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Dosing (usual): Treatment of ADHD in children and adolescents up to 70 kg body weight. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor BP. chlorpromazine, methylphenidate. Avoid or Use Alternate Drug. Monitor Closely (1)hydralazine, methylphenidate. Additive vasospasm; risk of hypertension. 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